'1945Establishment of the Model Public Health Center, Joseon Health Research Institute and National Chemical Laboratory
'1959Integration into the Central Institute of Health
'1966Name changed to the Korea National Institute of Health
'1981Name changed to the National Institute of Health and establishment of the Division of Human Immunodeficiency Virus (HIV)
'1996Separation of the Food and Drug Safety Headquarters and establishment of the Department of Special Diseases (currently, the Department of Chronic Disease Convergence Research)
'1998Integration of the National Institute for Social Welfare Training and establishment of the Department of Health and Welfare Training
'1999Establishment of the Department of Infectious Disease Management
'2004Reorganization and expansion into the Korean Centers for Disease Control and Prevention (KCDC) with the National Research Institute of Health (NIH) and 13 national quarantine stations
'2010Relocation to Osong (December) and establishment of the Division of Organ Donation Support, Division of Organ Transplant Management, and Center for Organ Transplant Management.
'2012Establishment of the Division of Vaccine Research and the National Biobank of Korea and expansion of the Korean Cohort Study and Research Infrastructure
'2014Establishment of the National Center for Medical Information Knowledge, the Division of Allergy and Respiratory Disease Research, and the Division of Medical Information Knowledge
'2016Elevation of the KCDC to the vice-ministerial level, establishment of the Emergency Operations Center (EOC), Director for Risk Communication, Division of Risk Analysis and International Cooperation, Division of Infectious Disease Diagnosis Control, and Team of General Affairs
'2017Reorganization of the KCDC with one bureau and four divisions created (the Bureau of Planning and Coordination, Division of Planning for Future Infectious Diseases, Division of Healthcare Associated Infection Control, Division of Chronic Disease Prevention, and Division of Rare Disease Management).
'2020Elevation to the Korea Disease Control and Prevention Agency (KDCA) and reorganization by adding one Vice Commissioner, three Bureau Directors, 16 Divisions, one Department, two Divisions, one Institute, five Regional Centers for Disease Control and Prevention, and one Office